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Clinical Profile of Cutaneous Adverse Drug Reactions in a Tertiary Care Centre

Priya Prathap, Elsy M.I, Ajitha K. N, Ajith Kumar, Sandhya George
DOI: http://dx.doi.org/10.21013/jas.v3.n3.p12
Abstract

Context: Cutaneous adverse drug reactions  (cADR) constitute 2-3% of all hospitalized patients. However there is paucity of data regarding occurrence of cADR among out patients. Hence we decided to do a study on clinical profile of cADR and to find out the common drugs resulting in cADR  .

Objective: To observe the clinical spectrum and the causative drugs of cADR  among patients attending  Dermatology Department in our hospital.

Methods: Patients with cADR who attended Dermatology Out Patient Department (OPD) in our institution  were studied for a period of one year.

Results:71 patients were diagnosed to have cADR. Male to female ratio was 1.15 :1. Maculopapular rash (22/71 ; 31%) was the commonest presentation followed by generalised pruritus (16/71; 22.5%) , fixed drug eruption( FDE) ( 8/71 ;11.3%) and urticaria (5/71 ;7%). Antimicrobials (40.8%), NSAIDS (22.5%) and  Antiepileptics (22.5 %) were the common drugs responsible for these eruptions.  

Keywords
antibiotics, antiepileptics, drug reactions
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