Email this article Peer Reviewed Open Access
This paper is reviewed in accordance with the Peer Review Program of IRA Academico Research
Biological Portfolio of 1,5-Disubstituted Tetrazoles: A Review
Abstract
The achievement of medicinal chemistry, in the last few decades, has intensively increased due to the creation of novel drugs withe isostericnature of tetrazole ring with carboxyl group in longer chain peptides was responsible for the medicinal activity. Therefore a comprehensive search was carried out for 1, 5-disubstituted tetrazoles owing to their synthetic and effective pharmacological activities such as anti-inflammatory, antiviral, antibiotic, anti-ulcer, anti-tubercular, anti-hypertensive, etc. In spite of many research papers in the area of tetrazoles with respect to their pharmacological activity there have been no review on1, 5-disubstituted tetrazoles inthis field. The aim of present review is to classify and summarize the pharmaceutical uses of 1, 5-disubstituted tetrazole containing compounds.
Keywords
1, 5-disubstituted tetrazoles, biological activities, isostere
Full Text:
PDF©IRA Academico Research & its authors
This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. This article can be used for non-commercial purposes. Mentioning of the publication source is mandatory while referring this article in any future works.
This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. This article can be used for non-commercial purposes. Mentioning of the publication source is mandatory while referring this article in any future works.
