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Pathophysiology of Giant Cell Formation in Giant Cell Tumor and Lesions: A Review

Samar Khan
Abstract
This review is intended to provide insight into the current state of understanding regarding the molecular and cellular mechanisms underlying the formation and function of various types of multinucleated giant cells. Present article mainly focus on various factors such as e.g. GCP/F, GM-CSF, Meltrin, MIP-1 that contribute to giant cell formation and function. This review focuses on recent efforts to develop a better understanding of the molecular and cellular biology of multinucleated giant cell formation and function.
Keywords
Multinucleated Giant Cell, Macrophage, Osteoclast. Macrophage inflammatory protein, Meltrin
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